Ⅳ型膠原α1(COL4a1)重組蛋白
Recombinant Collagen Type IV Alpha 1 (COL4a1)
COL4-A1; Arresten; Collagen Alpha-1(IV)chain
- 編號RPA149Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位分泌
- 預(yù)測分子量31.3kDa
- 實(shí)際分子量31kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Pro1416~Thr1669 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點(diǎn)7.8
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA149Ra01 | Ⅳ型膠原α1(COL4a1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA149Ra01 | Ⅳ型膠原α1(COL4a1)多克隆抗體 | WB; IHC; ICC; IP. |
| MAA149Ra21 | Ⅳ型膠原α1(COL4a1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEA149Ra | Ⅳ型膠原α1(COL4a1)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA149Ra | Ⅳ型膠原α1(COL4a1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Cancer Research | Peritoneal Dissemination Requires an Sp1-Dependent CXCR4/CXCL12 Signaling Axis and Extracellular Matrixa??Directed Spheroid Formation [Pubmed:26744523] |
| PLoS One | miR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes [10.1371] |
| Journal of Diabetes & Metabolic Disorders | Endothelin-1 traps potently reduce pathologic markers back to basal levels in an in vitro model of diabetes [] |
| Experimental and Molecular Pathology? | Epitope recognized by anti-glomerular basement membrane (GBM) antibody in a patient with repeated relapse of anti-GBM disease [Pubmed: 30817909] |
| Journal of Diabetes & Metabolic Disorders | In vivo studies demonstrate that endothelin-1 traps are a potential therapy for type I diabetes [] |
| Frontiers in Endocrinology | Curcumin Analogs Reduce Stress and Inflammation Indices in Experimental Models of Diabetes [Pubmed: 31920992] |
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