神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白
Recombinant Neuregulin 1 (NRG1)
ARIA; GGF; HGL; HRG; HRGA; NDF; SMDF; Acetylcholine receptor-inducing activity; Glial growth factor; Heregulin; Neu differentiation factor; Sensory and motor neuron-derived factor
- 編號RPB866Ra02
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位細胞膜, 分泌
- 預(yù)測分子量18.6kDa
- 實際分子量19kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Ser328~Lys486 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點7.3
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 864 ¥ 2160 ¥ 4320 ¥ 12960 ¥ 32400
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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SDS-PAGE圖
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通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPB866Ra01 | 神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB866Ra02 | 神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB866Ra03 | 神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB866Ra04 | 神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB866Ra02 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAB866Ra03 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAB866Ra01 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAB866Ra04 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體 | WB; IHC; ICC; IP. |
| LAB866Ra71 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| SEB866Ra | 神經(jīng)調(diào)節(jié)素1(NRG1)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| WEB866Ra | 神經(jīng)調(diào)節(jié)素1(NRG1)檢測試劑盒(酶聯(lián)免疫吸附試驗法,寬范圍) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB866Ra | 神經(jīng)調(diào)節(jié)素1(NRG1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Neuroscience Letter | Therapeutic effect of co-transplantation of neuregulin 1-transfected-Schwann cells and bone marrow stromal cells on spinal cord hemisection syndrom [Cyagen: source] |
| PLoS One. | ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis [PubMed: PMC3519469] |
| The Journal of Clinical Investigation | Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration [PubMed: PMC3428100] |
| Physiol Behav | Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress [PubMed: 26626816] |
| J Toxicol Sci.? | Effects of prolonged antipsychotic administration on neureCavia (Guinea pig )lin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect. [Pubmed:26961615] |
| journal of cellular and molecular medicine | Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway. [pubmed:28271613] |
| Transl Psychiatry. | Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation. [pubmed:28267150] |
| Human?Molecular?Genetics | A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas [Pubmed: 30335132] |
| Aging (Albany NY) | Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin [Pubmed: 32920546] |
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