密封蛋白(OCLN)重組蛋白
Recombinant Occludin (OCLN)
Tight Junction Protein Occludin TM4 Minus
- 編號(hào)RPC228Hu01
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位細(xì)胞膜
- 預(yù)測(cè)分子量33.8kDa
- 實(shí)際分子量42kDa(差異分析請(qǐng)參閱說(shuō)明書)
- 片段與標(biāo)簽Lys266~Thr522 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 90%
- 等電點(diǎn)5.5
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載 英文說(shuō)明書 中文說(shuō)明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價(jià)格 ¥ 840 ¥ 2100 ¥ 4200 ¥ 12600 ¥ 31500
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. Gene Sequencing (Extract)
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Figure. SDS-PAGE
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通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPC228Hu01 | 密封蛋白(OCLN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC228Hu01 | 密封蛋白(OCLN)多克隆抗體 | WB; IHC; ICC; IP. |
| MAC228Hu22 | 密封蛋白(OCLN)單克隆抗體 | WB; IHC; ICC; IP. |
| SEC228Hu | 密封蛋白(OCLN)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC228Hu | 密封蛋白(OCLN)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Brain Research | HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9 [ScienceDirect: S0006899311021408] |
| Plos one | Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation [PubMed: PMC3688973] |
| Journal of Neurotrauma | A new panel of blood biomarkers for the diagnosis of mild traumatic brain injury/concussion in adults [PubMed: 25794137] |
| United States Patent Application | Methods for Diagnosis and Treatment of Concussion or Brain Injury [2016:0103140] |
| Sci Rep.? | Blood Occludin Level as a Potential Biomarker for Early Blood Brain Barrier Damage Following Ischemic Stroke [articles:srep40331] |
| Frontiers in Pharmacology | Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal?… [Pubmed:29375374] |
| Thorax | Fas activation alters tight junction proteins in acute lung injury [Pubmed: 30385692] |
| Antioxidants (Basel). | The Effect of Dietary Quercetin on the Glutathione Redox System and Small Intestinal Functionality of Weaned Piglets [Pubmed: 31426309] |
| DISEASE MARKERS | Peripheral blood occludin level as a biomarker for preoperative cerebral edema in patients with brain tumors [Pubmed: 32884584] |
| Burns Open | Intestinal Permeability in Participants With Thermal Injury: A Case Series From a Prospective, Longitudinal Study (HESTIA) [] |
| PLoS One | A comparison of the effects of monotherapy with rosuvastatin, atorvastatin or ezetimibe versus combination treatment with rosuvastatin-ezetimibe and?… [34492054] |
| CNS Neuroscience & Therapeutics | Higher serum occludin after successful reperfusion Is associated with early neurological deterioration [Pubmed:35338575] |
| Impact de l'incorporation d'acides gras à chaine moyenne, de suppléments de levures et d'avoine nue sur la santé intestinale ainsi que sur la consommation?… [] |
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