高溫需求因子A1(HTRA1)重組蛋白
Recombinant High Temperature Requirement Factor A1 (HTRA1)
HtrA; L56; ORF480; PRSS11; HtrA Serine Peptidase 1; Protease,Serine,11; IGFBP5-Protease; High-temperature requirement A serine peptidase 1
- 編號(hào)RPL604Co01
- 物種Escherichia coli(大腸桿菌) 相同的名稱(chēng)，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位分泌
- 預(yù)測(cè)分子量15.4kDa
- 實(shí)際分子量16kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
- 片段與標(biāo)簽Ala10~Gly146 with N-terminal His Tag
- 緩沖液成份100mM NaHCO3, 500mM NaCl緩沖液（pH8.3,含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 97%
- 等電點(diǎn)5.7
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載 英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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SDS-PAGE圖
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通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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| 編號(hào) | 適用物種：Escherichia coli(大腸桿菌) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPL604Co02 | 高溫需求因子A1(HTRA1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPL604Co01 | 高溫需求因子A1(HTRA1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAL604Co01 | 高溫需求因子A1(HTRA1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAL604Co02 | 高溫需求因子A1(HTRA1)多克隆抗體 | WB |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Placenta | Alterations of maternal plasma HTRA1 level in preeclampsia complicated by IUGR [PubMed: 23083999] |
| Placenta | Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia [PubMed: 22964307] |
| Exp Gerontol | Association of frailty with the serine protease HtrA1 in older adults [Pubmed:27058767] |
| International Journal of?Clinical?and Experimental Pathology | HtrA1 up-regulates expression of MMPs via Erk1/2/Rock-dependent pathways [files:ijcep0069706.pdf] |
| Pregnancy Hypertension | Association between first trimester plasma htra1 level and subsequent preeclampsia: a possible early marker? [] |
| American journal of translational research | HtrA1 upregulates the expression of ADAMTS-5 in HNPCs via the ERK/NF-κB/JNK signaling pathway [Pubmed: 31497227] |
| J Matern Fetal Neonatal Med | First trimester HtrA1 maternal plasma level and spontaneous preterm birth [Pubmed: 32102578] |
| BMC Geriatr | Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population [33743591] |
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