滲透性糖蛋白(Pgp)重組蛋白
Recombinant Permeability Glycoprotein (Pgp)
CD243; ABCB1; ABC20; CLCS; GP170; MDR1; PGY1; P-Glycoprotein; Multidrug resistance protein 1; ATP-Binding Cassette,Sub-Family B(MDR/TAP),Member 1; Colchicin Sensitivity
- 編號RPB690Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位細胞膜, 分泌
- 預(yù)測分子量33.8kDa
- 實際分子量34kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Ala999~Ser1277 with N-terminal His Tag
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 90%
- 等電點9.1
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 816 ¥ 2040 ¥ 4080 ¥ 12240 ¥ 30600
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPB690Ra01 | 滲透性糖蛋白(Pgp)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB690Ra01 | 滲透性糖蛋白(Pgp)多克隆抗體 | WB; IHC; ICC; IP. |
| SEB690Ra | 滲透性糖蛋白(Pgp)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB690Ra | 滲透性糖蛋白(Pgp)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| International Forum of Allergy & Rhinology | P-glycoprotein promotes epithelial T helper 2–associated cytokine secretion in chronic sinusitis with nasal polyps [Onlinelibrary: alr.21316] |
| International Forum of Allergy & Rhinology | P‐glycoprotein regulates Staphylococcus aureus enterotoxin B–stimulated interleukin‐5 and thymic stromal lymphopoietin secretion in organotypic mucosal explants [PubMed: 26625351] |
| American Journal of Rhinology & Allergy | Intact?soluble?P-glycoprotein?is?secreted?by?sinonasal?epithelial?cells. [pubmed:27456593] |
| The Laryngoscope | Secreted P-glycoprotein is a noninvasive biomarker of chronic rhinosinusitis [pubmed:27577924] |
| Materials Science and Engineering: C | Design of colloidal drug carriers of celecoxib for use in treatment of breast cancer and leukemia [] |
| Molecular Cancer | Chemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in developing an urgent chemoresistance [Pubmed: 31830995] |
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